Immunohistochemical determinations of TNFα were made in sections of arterial territories obtained from 10 surgical PAD patients, namely 5 from patients with FGF23 serum levels above the median values in the whole population (high-FGF23 group ≥ 48.5 pg/mL) and 5 below this threshold (low-FGF23 group < 48.5 pg/mL). This evidence concerns the gene FGF23 and peripheral arterial disease.