Evaluating the effect of the APOL1 G1 variant, Ngo-Bitoungui et al. found a significant association between the rs71785313 variant and eGFR in children with SCA (beta 0.890305, p = 0.0461) [36], but this was not confirmed in adults with SCD [23]. The gene discussed is APOL1; the disease is Schnyder corneal dystrophy.