Most of the measured cytokine, chemokine, and growth factor concentrations (IL-1β, IL-2, IL-6 IL-10, IL-12p70, IL-17a, IFN-γ, TNF-α, GM-CSF, MCP-1) of the vehicle control were more elevated in the BALF than in the plasma on Day 3 post-infection (Figure 4 and Figure 5 and Figure S1 in the Supplementary Material), when the viral titers peaked (Figure 2) and as seen in other studies using this model (data on file at CRL). This evidence concerns the gene IFNG and infection.