The symptoms of psoriasis, such as thickness, erythema, and scaling, and the inflammatory cytokines levels of T-helper (Th)-17-specific cells, such as IL-17 and IL-22, and Th-1-specific cells, such as TNF-α and IL-1β, are reduced by treatment with L-EO in an IMQ-induced psoriasis mouse model [109]. This evidence concerns the gene TNF and psoriasis.