Research on telomerase activity in the nasopharyngeal carcinoma radioresistant cell line CNE-2R documented that the expression of stem cell-related genes (including CD133 mRNA) and the hTERT gene in radioresistant CNE-2R cells was higher than those in radiosensitive CNE-2 cells. The gene discussed is PROM1; the disease is nasopharyngeal carcinoma.