In contrast, consistent additive/synergic effects of MET or ASP with other compounds in relation to CRC have been found (namely, MET with rapamycin (sirolimus) [45], thymoquinone [46] or oxaliplatin [47] and ASP with platinum derivatives [19], selenium [48] and an anti-PD-L1 antibody [49]). Here, CD274 is linked to colorectal carcinoma.