The study showed that hypoxia related genes and the high-grade group of PCa had positive correlations as shown between P4HA1 gene and Angular Second Moment T2WI, Correlation T2WI, Sum Average T2WI, and Sum Square Variance T2WI, with coefficients ranging from 0.575 to 0.704, as shown in Figure 3. This evidence concerns the gene P4HA1 and posterior cortical atrophy.