CXCL8 and asthma: Since the IL-8 gene is absent in the mouse genome, we were not able to test the effect of 11,17diHDoPE on the IL-8 pathway, further studies using human cell lines, such as PM10-induced asthma or COPD cell lines, could be beneficial for understanding the role of 11,17diHDoPE in the PM10-induced IL-8 pathway.