LMNA and Emery-Dreifuss muscular dystrophy: According to the pattern of inheritance, two main forms of EDMD can be distinguished, an X-linked form (XL-EDMD, EDMD1) caused by mutation in emerin gene (EDM) [41,42], and an autosomal dominant form (AD-EDMD, EDMD2) caused by mutations in LMNA A/C gene [43].