To verify the relationship between dyslipidemia and the expression of LOX-1 in the vessels, cDNA clones were isolated from rabbit placenta that encoded the LOX-1 homolog, which maintains a highly conserved structure, and rabbit clones were transfected into HEK-293 cells; this procedure gave them the property of binding and internalizing ox-LDL; authors reported that LOX-1 accumulated in rabbit aortas (with hereditary hyperlipidemia) compared to rabbit aortas control [79]. This evidence concerns the gene OLR1 and hyperlipidemia.