NFKB1 and obesity due to melanocortin 4 receptor deficiency: As is the case with dyslipidemia, we can also point out that proinflammatory cytokines are dependent on the expression of LOX-1 due to the positive regulation of the NF-κB factor, which triggers this sterile and low-grade inflammation, related to other disorders, such as obesity, where the increase in blood lipids and pathologies such as diabetes mellitus, metabolic syndrome, and hypertension are implicit, which are related to this inflammation.