This brain-derived neurotrophic factor (BDNF) participates in axonal growth, pathfinding, and the modulation of dendritic growth and morphology, being a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the central nervous system, so that it has been tentatively implicated in the pathogenesis of epilepsy [67]. Here, BDNF is linked to epilepsy.