TNF and Sepsis: The most common biomarkers of sepsis include increased procalcitonin (early sepsis indicator), increased C-reactive protein, inflammatory cytokines (TNF-α and IL-6), monocyte chemoattractant protein-1 (MCP-1), complement pathway activation, neutrophil surface receptor (CD64), angiopoietin, MMPs, and many more to patient recovery and survival [79,80].