Univariable logistic regression analyses showed that TAC C0 (OR: 0.84, 95% CI: 0.725–0.972, p = 0.019) and fast metabolizer type at six months (OR: 2.141 95% CI: 1.044–4.389, p = 0.038), along with several clinical factors, namely, donor age, donor hypertension, duration of renal replacement therapy before transplantation, cold ischemia time, usage of angiotensin-converting enzyme (ACE) inhibitors at one year after transplantation, and IF/TA progression in surveillance biopsies, were significantly associated with 1-year eGFR. This evidence concerns the gene ACE and Hypertension.