Similarly, the FGFR2-targeting mAb PRO-007 reduced proliferation, invasiveness and MAPK signalling in FGFR2-amplified Kato III GC cells in vitro; however, details regarding its FGFR2 isoform specificity and ability to inhibit FGF-induced FGFR2 stimulation were not provided [112]. Here, FGFR2 is linked to gastric cancer.