Of note, these cells also expressed higher levels of HLA class II (HLA-DOA, HLA-DMA, HLA-DOB, HLA-DMB,) FC receptors (FCRLA and FCRL1), MSR1 (scavenger receptor), and KLRF1 (C-type lectin-like receptor), suggesting that circulating neutrophils in severe MASH may have the increased recognition and clearance of apoptotic cells and pathogens and antigen-presenting functions. Here, FCRLA is linked to metabolic dysfunction-associated steatohepatitis.