Most of the protein hits could be identified in blood samples according to the HPA database; two of them, namely DPEP1 and SOST, were classified by HPA as upregulated in BC; and five of them were found to be upregulated in leukemia and myeloma: SOST, TXNRD1, PKLR, EPHA2, PLIN3. The gene discussed is PKLR; the disease is breast cancer.