As shown in Figure 1, we detected caspase-3 positive cardiomyocytes (Figure 1A,B) and caspase-3 positive fibroblasts (Figure 1C,D) in the infarct border zone of mice that underwent acute myocardial infarction using cardiac sections of the LV at day 5 post-I/R. Here, CASP3 is linked to myocardial infarction.