APC and lung carcinoma: Other genes such as fibroblast growth factor receptor (FGFR), ataxia telangiectasia mutated (ATM), cyclin-dependent kinase 12 (CDK12), hepatocyte nuclear factor 1 alpha (HNF1A), adenomatous polyposis coli (APC), and tumor protein 53 (TP53) have also been implicated in lung cancer bone metastasis [224].