Bioinformatic prediction results revealed that the miRNAs analyzed may potentially be involved in the regulation of several lung cancer driver genes, such as BCL2, CYCS, E2F3, MCL1, MFN2, MYC, RNF115, SENP1, SLC1A5, SLC6A4, SLC7A11, and TMOD3, which are involved in cancer key regulatory pathways [63,64,65,66,67,68,69,70,71,72,73,74,75]. The gene discussed is RNF115; the disease is cancer.