The median RANKL level did not significantly differ between Arab people with T2D (0.01 (13.43) pg/mL) and those without diabetes (5.13 (12.18) pg/mL), but these medians were significantly higher for Asian individuals with T2D (17.3 (63.9) pg/mL) compared to those for with those without diabetes (0.01 (6) pg/mL, p < 0.001). Here, TNFSF11 is linked to type 2 diabetes mellitus.