In comparison with levels in SVGp12, the average increases in PGC-1α expression in various glioma cell lines were as follows: 5.4-fold in GBM8401 cells, 1.7- to 2-fold in U87-MG cells at different time points, and approximately 4.6-fold in A172 cells. Here, PPARGC1A is linked to central nervous system cancer.