PGC-1α expression levels in the glioma cell lines GBM8401, U87-MG, G5T/VGH, DBTRG-05MG, M059K, and A172 were significantly higher than those in SVGp12, suggesting that PGC-1α in integral in the pathogenesis of glioma. This evidence concerns the gene PPARGC1A and glioma.