Figure 2A shows that serum eNAMPT levels were significantly elevated in experimental NEC (p < 0.05), a finding corroborated by significant elevations in both NAMPT mRNA levels (p < 0.05) (Figure 2B) and NAMPT protein immunoreactivity in ileal tissues (p < 0.05) (Figure 2C). NAMPT expression levels in blood and ileal tissues were significantly reduced in the NEC + mAb group (p < 0.01) (Figure 2B,C). This evidence concerns the gene NAMPT and necrotizing enterocolitis.