The cytokine levels in patients with double infection were also reduced when compared to groups with HIV and TB alone; 11.1 times against the group with HIV monoinfection and 14.8 times against the group with TB monoinfection (p < 0.0001 and p < 0.0001, respectively; Figure 1C); however, between the two groups with HIV/TB, there was no difference in IL-10 production. This evidence concerns the gene IL10 and tuberculosis.