HDAC4 and metastatic malignant neoplasm in the lymph nodes: Similarly, tumors without lymph node metastasis were positive for HDAC-4 more frequently compared with tumors with lymph node metastasis, which was an association that was, however, of borderline significance in serous tumors, as well as in the entire cohort (Chi-square test, p = 0.069 for the entire cohort, p = 0.098 for serous tumors).