Based on the analysis of clinical and translational data, we propose diagnostic lncRNA fingerprint for GBM, which combines ANRIL (↑), HOTAIR (↑), LINC00641 (↑), LINC00565 (↑), MALAT1 (↑), SAMMSON (↑), and GAS5 (↓). Here, HOTAIR is linked to glioblastoma.