In detail, a population of children with AD underwent a four-food SPT (egg white, peanut, and sesame, as well as cow’s milk or crustacean) and then were subjected to further follow-up where, in addition to repeating the SPT, serum allergen-specific IgE was measured and oral food challenges to peanut, egg white, or sesame were performed. Here, IGHE is linked to Alzheimer disease.