Quite recently, a study from Thailand revealed higher frequencies (AFs) of HLA-DRB1*15:02:01, DRB5*01:02:01, DQB1*05:01:24, DPB1*13:01:01, and DQA1*01:01:01 in all SSc patients as well as in SSc subjects with positive ATA, but with negative ACA (SSc/ATA+/ACA-) [39]. Here, HLA-DRB1 is linked to systemic sclerosis.