SLK and uterine corpus leiomyoma: In another GWAS conducted on individuals of Han Chinese descent, a variant in STE20-like kinase (SLK) increased the risk of UL development via a mechanism independent of age at menarche, while another variant in HLA class II histocompatibility antigen, DO beta chain (HLA-DOB) decreased the risk through its association with age at menarche [46].