SYNE1 and breast cancer: Additionally, hormone-associated genes, also observed in endometriosis and breast cancer, have been associated with UL, including cell division cycle 42 (CDC42/WNT4), GREB1, minichromosome maintenance 8 homologous recombination repair factor (MCM8), and spectrin repeat containing nuclear envelope protein 1 (SYNE1/ESR1) [41].