Targeted sequencing of multigene panels in next-generation sequencing for genes associated with cortical dysplasia highlighted the presence of the c.151A>G(p.(Met51Val)) variant in the DCX gene (MIM*300121) and c.1186G>A(p.(Val396Ile)) in the PAFAH1B1 gene (MIM*601545), both paternally inherited. Here, PAFAH1B1 is linked to cerebral cortical dysplasia.