Consistently, reducing the levels of miR‐103a‐3p, an miRNA that is abundantly present in models of PD generated by MPTP, reduces the degradation of DopNs in the SN and enhances walking difficulties by initiating the process of mitophagy mediated by the PRKN/Ambra1 pathway.111, 127. The gene discussed is PRKN; the disease is Parkinson disease.