Specifically, concentrations of CC chemokines (CCL1, CCL4, CCL7, CCL8, CCL11, CCL13, CCL15, CCL19, CCL2, CCL20, CCL21, CCL22, CCL23, CCL24, CCL25, CCL26 and CCL27) and CXC chemokines (CXCL2, CXCL5, CXCL6, CXCL8, CXCL9, CXCL10, CXCL11, CXCL12, CXCL13, CXCL16 and CX3CL1) were higher in the diabetic eye disease patients than in the controls. This evidence concerns the gene CXCL16 and diabetic eye disease.