(Fig. 7A) Based on the amount of PD-L1 expressed by immune cells (IC0, IC1 and IC2 + subgroups) or tumor cells (TC0, TC1 and TC2 + subgroups) and the level of CD8 T cell infiltration in TME (desert, excluded and inflamed subgroups), patients were divided into subgroups. The gene discussed is CD8A; the disease is neoplasm.