In contrast, the enriched pathways of the downregulated genes included those related to DNA damage repair, such as “Nucleotide excision repair (NER) Enhanced Pathway,” “Hereditary Breast Cancer Signaling,” and “Role of BRCA1 in DNA Damage Response” (−log(p value) = 9.27, 8.51 and 7.38, respectively) (Fig. 3b). Here, BRCA1 is linked to breast carcinoma.