CD8A and neoplasm: To define whether the change in proliferation is a broad impact across all T cells or a result of changes in specific T cell populations following radiation therapy, we used graph-based clustering to identify 5 major subpopulations of CD8 T cells in the tumors (clusters 1, 2, 3, 4, and 5) among other tumor infiltrating immune cells (Supplemental Fig. 7, Fig. 4bi).