In DF enteroids, T1D had lower expression of CFTR, DRA, SI and increased expression of NHERF2 but no significant change in expression of E-cadherin, myosin 5C, sodium-glucose cotransporter-1 (SGLT-1), NHE2, ALP1 or NHERF1 (Fig. 3b). The gene discussed is NHERF1; the disease is type 1 diabetes mellitus.