COG2 and hyperlipidemia: For example, a 12-week treatment with L plantarum Q180 for effectively reduced the levels of LDL-C and apolipoprotein (Apo)B-100.[10]L curvatus HY7601, as well as L plantarum KY1032 downregulated TG.[24] The probiotic B longum strain BL1 reduced TC and TG levels.[25] The current study performed double-blind RCT using patients with hyperlipidemia with the aim of observing altered intestinal flora and exploring the relationship between intestinal flora and blood lipid changes using a probiotic consisting of L casei Zhang, B animalis subsp.