In another cohort of 150 children with AKI following cardiac surgery, the biomarkers showed an increasing order: urine NGAL (2 hours after surgery) > urine IL-18 and urine L-FABP, urine TIMP-2, and IGFBP-7 (6 hours after surgery) > urine KIM-1 (12 hours postoperatively). The gene discussed is IL18; the disease is acute kidney injury.