CSF2 and neoplasm: We also incorporated various immunotherapeutic moleculesinto TRGs, eliminating initial CT-26 tumors and preventing lung metastasis.The findings emphasize that TRG is highly effective in treating primarytumors and preventing both development and reappearance.187 Wang et al. demonstrated that injecting macroporousalginate gels around the tumor site (loaded with granulocyte-macrophagecolony-stimulating factor (GM-CSF) to concentrate dendritic cells(DCs), CpG oligonucleotides, and a doxorubicin-iRGD conjugate) enhancesthe death of tumor cells by immune responses.