Four genes previously thought to influence the severity of Guillan–Barré syndrome (GBS) [88,89,90] were affected differently but moderately (PTGS2, Fc.: 1.188×; ANXA3, Fc.: 1.31×; CREB1, Fc.: 1.73×) by the 3rd hour of infection (Table 5). The gene discussed is CREB1; the disease is Guillain-Barre syndrome.