Therefore, the aim of the present study was to investigate the protein and mRNA expression levels of relevant inflammatory cytokines, the renal NaPi-IIa cotransporter and the TRAIL-induced apoptosis mediators TRIAL, CASP3 and CASP8 in both the blood and kidney of experimental mice affected by malaria-associated AKI. The gene discussed is TNFSF10; the disease is acute kidney injury.