CD274 and gastric cancer: In a post hoc analysis of the ITACA-S trial (sequential chemotherapy regimen vs. 5-FU/LV monotherapy as adjuvant treatment in patients with radically resected GC), microsatellite instability (MSI) was found to have a positive prognostic value with better disease-free survival and overall survival; even inflammatory reactions were related to better overall survival, prognostic, and predictive value of MSI, inflammatory reaction, and PD-L1 in GC.