No difference was found for the TNF-α levels (p = 0.86) between dogs with uncontrolled diabetes, with a median of 594 pg/mL (IQR, 107–1210; range, 49–3510 pg/mL), and controlled with a median of 677 pg/mL (IQR, 128–1164; range, 48–5048 pg/mL). This evidence concerns the gene TNF and diabetes mellitus.