Even the etiopathogenetic mechanism of euDKA in patients taking an SGLT2-i is not fully understood yet, although an important role is surely played by precipitating factors, such as infections, concurrent pathologies, the post-operative stage, a reduction in caloric and/or fluid intake, alcohol abuse, a low-carbohydrate diet and a significant reduction in the daily insulin dose. Here, SLC5A2 is linked to alcohol abuse.