Similar results had been noticed by Antoniak-Pietrynczak et al., 2023, where no statistically significant correlations between the BMI and the concentration of FPG, HbA1c, hsCRP, TG, IL-10 and Adiponectin concentration were found in patients with overweight and obesity [21]. The gene discussed is ADIPOQ; the disease is obesity due to melanocortin 4 receptor deficiency.