When linked to the carboxyl terminus of p53, the 21-amino acid peptide antennapedia (p53p-Ant) inhibits cell proliferation in correlation with p53 expression levels in human (mut-p53 U138 and wt-p53 U87MG) and rat (F98 and D74, both with mut-p53) glioma cells [342]. This evidence concerns the gene TP53 and central nervous system cancer.