Apigenin sensitized glioma to radiotherapy by inhibiting glycolytic enzymes and the expression of NF-κB, p65, HIF1α, GLUT-1/3, and pyruvate kinase isozyme type M2 (PKM2) in human GSCs and a subcutaneous glioma model (Table 1). The gene discussed is SLC2A1; the disease is central nervous system cancer.