Interestingly, Linc01060 (long noncoding RNA) isolated from exosomes derived from glioma stem cells under hypoxia were found to promote progression in glioma cells by facilitating aerobic glycolysis, inducing HX, PGK1, and LDHA expression, as well as Glu uptake, and increasing lactate and ATP levels [294]. Here, PGK1 is linked to central nervous system cancer.