CCL2 and cancer: On the other hand, Khosravi et al. [50], which included 27 studies with 1190 participants aged 27 to 70 years old, mentioned that aerobic, resistance, and combined exercises, predominantly performed by women diagnosed with cancer, led to an increase in monocyte chemoattractant protein 1 (MCP-1) levels and a modest decrease in pro-inflammatory markers CRP and TNF.