CD274 and digestive system cancer: Based on the obtained results in our study, most samples showed a percentage of positivity between 5 and 10: 36 of them (35.3%); therefore, we believe that our proposal for the threshold value for assessing PD-L1 positivity in CRC would be values ≥ 10, although the cut-off value for gastrointestinal tract cancers approved by the FDA using the CPS method is ≥1.