Findings indicated that, independent of B/F/TAF treatment, EcoHIV infection reduced the expression of IL-6 and LIF in plasma, compared to sham mice [IL-6 (Figure 4A): main effect of EcoHIV: F (1, 39) = 4.804, p = 0.0344; no main effect of B/F/TAF: F (1, 39) = 0.8515, p = 0.3618; no interaction: F (1, 39) = 0.8436, p = 0.3640; LIF (Figure 4B): main effect of EcoHIV: F (1, 34) = 4.768, p = 0.0360; no main effect of B/F/TAF: F (1, 34) = 0.001303, p = 0.9714; no interaction: F (1, 34) = 0.006513, p = 0.9362]. This evidence concerns the gene LIF and infection.