The most recent classifications identify Luminal-A (ER+/PR+, HER2−), Luminal-B (ER+/PR±, HER2+), HER2-enriched (ER−/PR−, HER2+), and Basal-like (ER−/PR−, HER2−) breast tumors. The gene discussed is ERBB2; the disease is breast neoplasm.