The miR-18a/low tumours had higher expression of the luminality-associated genes like ESR1, GATA3, FOXA1, XBP1 and TFF1 and a lower expression of the basality-associated genes such as KRT18, KRT17, FOXC1, ANLN, STIL and MIA (p < 0.05) (Figure 1C). The gene discussed is XBP1; the disease is neoplasm.