However, the disease-free survival was significantly different between the ER-positive/miR-18a/low tumours vs. ER-negative/miR-18a/low tumours (p = 0.001) and the ER-positive/miR-18a/high tumours vs. ER-negative/miR-18a/low tumours (p = 0.001). This evidence concerns the gene ESR1 and neoplasm.